Ukuqhathaniswa kwezindlela ezimbili zokutholwa zokuthola i-SARS-CoV-2 receptor ebophezelayo yesizinda se-IgG njengomaka wokuhlola amasosha omzimba angathathi hlangothi ezigulini ze-COVID-19.

I-Int J Infect Dis.Juni 20, 2021: S1201-9712(21)00520-8.doi: 10.1016/j.ijid.2021.06.031.Ku-inthanethi ngaphambi kokuphrinta.
Isendlalelo: Amasosha omzimba angathathi hlangothi (NAbs) abalulekile ukuvikela ukuphinda utheleleke nge-COVID-19.Siqhathanise ukuhlolwa okubili okuhlobene ne-NAb, okuyi-hemagglutination test (HAT) kanye ne-replacement virus neutralization test (sVNT).
Izindlela: Ukucaciswa kwe-HAT kwaqhathaniswa ne-sVNT, futhi ukuzwela nokuqina kwamasosha omzimba ezigulini ezinobunzima obuhlukile besifo kwahlolwa eqenjini leziguli ze-71 kumaviki angu-4 kuya kwangu-6 kanye namaviki angu-13 kuya kwangu-16.Ukuhlolwa kwe-kinetic kweziguli ezinezifo ezinzima zobunzima obuhlukene kwenziwa evikini lokuqala, lesibili nelesithathu.
Imiphumela: Ukucaciswa kwe-HAT ngu>99%, futhi ukuzwela kuyefana nalokho kwe-sVNT, kodwa kuphansi kunaleyo ye-sVNT.Izinga le-HAT lihlotshaniswa kahle kakhulu nezinga le-sVNT (i-Spearman's r = 0.78, p<0.0001).Uma kuqhathaniswa neziguli ezinesifo esingatheni, iziguli ezinezifo ezilinganiselayo nezinzima zineziqu eziphakeme ze-HAT.Iziguli ezingu-6/7 ezigula kakhulu zinesihloko esingu->1:640 esontweni lesibili lokuqala, kuyilapho iziguli ezigula kancane ezingu-5/31 kuphela ezine-titer> 1:160 ngesonto lesibili lokuqala.
Isiphetho: Njengoba i-HAT iyindlela yokuthola elula futhi eshibhile, ilungile njengenkomba ye-NAb ezindaweni ezingenazo izinsiza.