Ikhithi Yokuhlola Esheshayo Ye-COVID-19 (i-Colloidal Gold)

Incazelo emfushane:

Imininingwane Yomkhiqizo

Inhloso yokusebenzisa:

◆Ukuze kutholwe amasosha omzimba angathathi hlangothi.

◆ I-COVID-19 Neutralizing Antibody Rapid Test Kit (Colloidal Gold) iyisivivinyo sokugeleza sangemuva esihloselwe ukutholwa kwekhwalithi ye-antibody ye-SARS-CoV-2 egazini lonke lomuntu, i-serum noma i-plasma njengosizo emazingeni Okuhlola ama-anti-body. - I-coronavirus entsha inciphisa i-antibody titer.

Indlela yesampula

◆Igazi Eliphelele, ISerum, I-Plasma

Isimiso sokusebenza:

◆Le kit isebenzisa i-immunochromatography.Ikhadi lokuhlola liqukethe:1)i-colloidal gold-leable recombinant novel coronavirus S-RBD antigen kanye nezimpawu zegolide ze-antibody zokulawula ikhwalithi;2) umugqa owodwa wokutholwa (umugqa we-T) kanye nomugqa owodwa wokulawula ikhwalithi (umugqa C) we-nitrocellulose membrane.Ulayini we-T awunyakazi nephrotheni ye-Human ACE2 yokuthola i-antibody eshintshashintshayo ye-coronavirus futhi umugqa we-C awunyakazi nge-antibody elawula ikhwalithi.

◆Uma inani elifanele lesampula lokuhlola lengezwa emgodini wesampula wekhadi lokuhlola, isampula lizoqhubekela phambili eduze nekhadi lokuhlola ngaphansi kwesenzo se-capillary.Uma isampula liqukethe i-antibody entsha ye-coronavirus, i-antibody izobophezela ku-colloidal yegolide ebhalwe ukuthi i-coronavirus antigen.I-antigen ye-coronavirus esele ebhalwe ngegolide ku-immune complex izobanjwa iphrotheni yomuntu ye-ACE2 engakwazi ukuhamba.

ulwelwesi ukwenza umugqa we-T onsomi-obomvu, ukushuba komugqa ongu-t Ngokuphambene ngokulingana nokuhlangana kwe-antibody.

◆Ikhadi lokuhlola liqukethe nomugqa wokulawula ikhwalithi C .Umugqa wokulawula ikhwalithi ye-fuchsia kufanele uvele kungakhathaliseki ukuthi umugqa wokuhlola uyavela yini.Uma ulayini wokulawula ikhwalithi C ungaveli, umphumela wokuhlolwa awuvumelekile, futhi isampula idinga ukuhlolwa futhi ngelinye ikhadi lokuhlola.

Imininingwane yomkhiqizo:

◆Severe acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2, noma 2019-nCoV) igciwane le-RNA elimboziwe elingahlukanisiwe.Yilokhu

imbangela ye-COVID-19, ethelelanayo kubantu.

◆SARS-CoV-2 inamaprotheni esakhiwo amaningana ahlanganisa i-spike (S), imvilophu (E), ulwelwesi (M) kanye ne-nucleocapsid (N).Iphrotheni ye-spike (S) iqukethe isizinda esibopha i-receptor (RBD), esibophezelekile ukuqaphela isamukeli sendawo yeseli, ama-antigen ekuguquleni i-enzyme-2 (ACE2).Kutholakala i-uman ACE2 receptor eholela ku-endocytosis kumaseli aphethe wamaphaphu ajulile kanye nokuphindaphindeka kwegciwane.

◆Ukutheleleka ngomgomo we-SARS-CoV-2 noma i-SARS-COV-2 kuqalisa impendulo yokuzivikela komzimba ukuze kukhiqizwe amasosha omzimba anikeza isivikelo ekuthelelekeni okuzayo kumagciwane.Amasosha omzimba anciphisa amandla abantu aqondise kusizinda sesizinda se-ACE2 receptor-binding (RBD) se-SAR-COV-2 spike protein akhombisa ukuthembisa ngokwelashwa nangempumelelo ngokuvikela.

◆I-Serum noma i-plasma specimen/igazi lomunwe.

◆Ngokutholwa kwe-semi-quantitative ye-antibody ehlukanisayo.

◆Ukuhlolwa kwe-antibody okungathathi hlangothi kungathola ukuthi akhona yini amasosha omzimba angathathi hlangothi ngokumelene ne-SARS-CoV-2 emzimbeni.

◆Siza ukulandelela ubude besikhathi sokugonywa kokuzivikela ngemva kokugoma.